Anti-AIF1 Antibody | Gentaur

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SKU:
544-MBS242148-GEN
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£340.00
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Description

Anti-AIF1 Antibody

Antibodies that detect IBA1 can be used in several scientific applications, including Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Flow Cytometry and ELISA.

These antibodies target IBA1 in Human, Rat and Mouse samples. Our IBA1 polyclonal, monoclonal, recombinant monoclonal and recombinant polyclonal antibodies are developed in Rabbit, Mouse, Goat and Rat.

These antibodies have been verified by Relative expression, Cell treatment and Knockout to confirm specificity to IBA1. Find the IBA1 antibody that fits your needs.

Quality Level

100

biological source

mouse

antibody form

purified antibody

antibody product type

primary antibodies

clone

20A12.1, monoclonal

species reactivity

mouse, human, rat

packaging

antibody small pack of 25 μg

technique(s)

immunohistochemistry: suitable
western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_001614

The allograft inflammatory factor-1 (AIF-1) is a 17 kDa interferon-gamma (IFN-gamma) inducible Ca(2+)-binding EF-hand protein that is encoded within the HLA class III genomic region. AIF-1 is known to be identical with ionized Ca(2+)-binding adaptor 1, microglia response factor-1, and daintain. AIF-1 expression is mostly limited to the macrophage/monocyte lineage, and is augmented by cytokines, such as IFN-gamma.

It is reported to be involved in neuronal function, inflammatory responses, allograft rejection, autoimmunity, and the activation and function of macrophages. It is also shown to be expressed in macrophages and microglial cells in autominnume disesases such as experimental autoimmune encephalomyelitis, and neuritis and uveitis models.

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Additional Information

Size:
100 µg
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