Mouse Anti-nucleosome recombinant Antibody
Species Reactivity Human
Host/Isotype Rabbit / IgG
Immunogen Recombinant protein corresponding to Human RCL
Purification Antigen affinity chromatography
Storage buffer PBS, pH 7.2, with 40% glycerol
Contains 0.02% sodium azide
Storage conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
Immunogen sequence: QPSLGVGYEL GRAVAFNKRI LCLFRPQSGR VLSAMIRGAA DGSRFQVWDY EEGEVEALLD RYFEADPPGQ
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 86%.
RCL was identified on the basis of its stimulation by c-Myc protein. The latter is a transcription factor that participates in the regulation of cell proliferation, differentiation, and apoptosis. The exact function of this gene is not known but studies in rat suggest a role in cellular proliferation and c-Myc-mediated transformation.