Phospho-NFAT2 (Ser294) Antibody | Gentaur

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SKU:
796-AF8012-GEN
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£340.00
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Description

Phospho-NFAT2 (Ser294) Antibody

Species Reactivity Human, Mouse

Host/Isotype Rabbit / IgG

Class Polyclonal

Type Antibody

Immunogen A synthesized peptide derived from human NFAT2 (Phospho-Ser294)

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Conjugate Unconjugated

Form Liquid

Concentration 1 mg/mL

Purification Affinity chromatography

Storage buffer PBS, pH 7.4, with 50% glycerol

Contains 0.02% sodium azide

Storage conditions -20°C

RRID AB_2663601

Product Specific Information

Phospho-NFATC2 (Ser294) Polyclonal Antibody detects endogenous levels of NFATC2 only when phosphorylated at Ser294.

Target Information

The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice variants, have been described: NFAT1 (also known as NFATp or NFATc2), NFAT2 (NFATc or NFATc1), NFAT3, and NFAT4 (NFATx or NFATc3).

These proteins show a low level of sequence similarity with the Dorsal/Rel/NFkB family of transcription factors. Another NFAT-related protein termed NFAT5 differs from isoforms 1-4 in that it lacks many of the Fos/Jun contact sites observed in its predecessors and its subcellular localization is not calcineurin-dependent.

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Additional Information

Size:
100 µg
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